Alan C. Farney, M.D., Ph.D., Associate Professor
Dr. Farney was born in Phoenix, Arizona, and grew up in Rochester, New York. Between 1979 and 1983 he attended Haverford College in Haverford, Pennsylvania, where he earned a Bachelor of Arts degree in Biology. In 1987 he was awarded the M.D. degree at the University of Rochester School of Medicine and Dentistry. Between 1987 and 1997 Dr. Farney matriculated at the University of Minnesota where he completed a residency in General Surgery in 1995, an abdominal organ Transplant Fellowship in 1997, and a Ph.D. in 1998 after working the laboratory of Dr. David Sutherland. In 1997, he joined the University of Maryland as Director of Islet Transplantation at the rank of Assistant Professor. He developed the human islet laboratory at the University of Maryland, obtained an IND for islet transplantation in humans, and performed the first islet transplants at the University of Maryland in 2002. Clinical duties included renal transplantation, pancreas transplantation, and pediatric renal transplantation. In August 2003 he moved to Winston-Salem, joining the faculty at the Wake Forest School of Medicine as an Associate Professor in General Surgery with a cross-appointment in the Wake Forest Institute of Regenerative Medicine. Dr. Farney is currently Clinical Director of Pancreas Transplantation, Islet Transplantation, and Pediatric Renal Transplantation.

SYNOPSIS OF AREA OF INTEREST:: Dr. Farney is interested in both clinical and basic science research. Clinical interests include study of new immunosuppressive regimens for renal and pancreas transplantation, steroid and calcineurin inhibitor avoidance in immunosuppressive protocols, quality of life and the effect of psychosocial risk factors on transplant outcomes, and outcomes after pediatric transplantation. Interests in basic science include islet of Langerhans physiology and immunology, islet transplantation and preservation.

PUBLICATIONS:

Farney AC, Najarian JS, Nakhleh RE, Lloveras G, Field JF, Gores PF, Sutherland DER. Autotransplantation of dispersed pancreatic islet tissue combined with total or near-total pancreatectomy for treatment of chronic pancreatitis. Surgery 1991;110(2):427-439

Farney AC, Xenos ES, Widmer MB, Stephanian E, Field MJ, Kaufman DB, Stevens RB, Blazar BR, Platt J, Sutherland DER, Gores PF. Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor. Transplantation Proceedings 1993; 25(1Pt1) :865-866.

Farney AC, Hering BJ, Nelson L, Tanioka Y, Gilmore T, Leone J, Wahoff D, Najarian JS, Kendall D, Sutherland DER. No late failures of intraportal human islet autografts beyond 2 years. Transplantation Proceedings 1998;30(2):420.

Farney AC, Cho E, Schweitzer EJ, Dunkin B, Philosophe B, Colonna J, Jacobs S, Jarrell B, Flowers JL, Bartlett ST. Simultaneous Cadaver Pancreas-Living Donor Kidney Transplantation: A New Approach for the Type 1 Diabetic Uremic Patient. Annals of Surgery 2000; 232(5):696-703.

Okitsu T, Bartlett ST, Hadley GA, Drachenberg CB, Farney AC. Recurrent autoimmunity Accelerates destruction of minor and major histoincompatible islet grafts in non-obese diabetic (NOD) mice. American Journal of Transplantation 2001; 1(2): 138-145.

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